Topics and Expertise: computational biology

Brian Shoichet, PhD, faculty member in the School’s Department of Pharmaceutical Chemistry, has been named the 2017 recipient of the DeLano Award for Computational Biosciences.

Bacteria generate small molecules to fend off their fellow microbes. They also produce molecules that affect the response of host organisms—including humans—to their presence. Such molecules have been a major source of antibiotics, immunosuppressants, anti-cancer agents, and other drugs.

How does brain circuitry organize itself during development? In at least one case—the seemingly complex visual system of the fruit fly, which connects its 800-facet compound eyes to its brain—the answer lies in just three simple rules.

Table of contents

Introduction
Budget significance
Reasons for past success
A decade of funding for bioinformatics
New drug discovery directions attract support
Research stalwarts draw funding for decades
New directions in translational research attract support
Expansion of the School’s...